Puma Biotechnology Inc Common Stock. Replay the stock market charts of PBYI day by day, back to 2003. Open long and short positions without spending any money. Puma Biotechnology Inc is a biopharmaceutical company. It is engaged in the acquisition, development and commercialization of products to enhance cancer care. Its drug candidates are PB272 (neratinib, oral), PB272 (neratinib, intravenous), and PB357.